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Canada Pulls Anti-Depressant Off Shelves

Nov 24, 2003 | Canadian Press a href="">More information on Serzone side effects

An anti-depressant drug called nefazodone is being pulled from the market because it has been linked to serious liver damage, Health Canada says.

"This risk, while very remote, poses a greater risk than other similar anti-depressants currently available in Canada," the federal department said.

Nefazodone is a prescription-only product approved in 1994 and sold under the trade name Serzone by Bristol-Myers Squibb Canada Inc.

It is also sold under the generic names Lin-Nefazodone, Apo-Nefazodone, Nefazodone, Dom-Nefazodone, Novo-Nefazodone-5HT2, PMS-Nefazodone and Gen-Nefazodone.

Health Canada says it is aware of 38 Canadian cases of liver-related adverse effects, including one death, believed to be associated with the drug from 1994 until the end of last year.

Bristol-Myers Squibb and Linson Pharma agreed to have their products withdrawn by Thursday.

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