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Glaxo to Reformulate Poli-Grip Denture Creams with Zinc in Canada

Feb 24, 2010 | Parker Waichman LLP

Citing health risks from zinc, GlaxoSmithKline has stopped the manufacture, distribution and advertising of Poli-Grip ‘Advanced Care’, ‘Extra Strength’ and ‘Ultra Fresh’ denture adhesives in Canada.

According to a Health Canada advisory to health care professionals, the decision was made because recent publications and reports suggest that excessive exposure to zinc in denture creams can lead to the development of myeloneuropathy and blood dyscrasias.  Neurological symptoms may include sensory disturbance, limb weakness and difficulty walking.

Consumers who have been using zinc-containing Poli-Grip ‘Advanced Care’, ‘Extra Strength’ or ‘Ultra Fresh’ for several years in greater amounts than directed on the package or more than once per day, or have concerns about their health, must:

1. Stop using the product.

2. Talk to their doctor.

3. Switch to a zinc-free alternative.

People with ill-fitting dentures should seek help from their dental care professional, rather than compensate for poorly fitting dentures by using excessive adhesive, Health Canada said.

As we reported last week, Glaxo has also ended the manufacture, distribution and advertising of three Super PoliGrip denture creams – ‘Original’, ‘Ultra Fresh’ and ‘Extra Care’ – in the U.S. over similar concerns. Glaxo will be introducing zinc-free versions of the denture adhesives in both the U.S. and Canada.


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