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Date you started taking this drug:

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What condition was this medication prescribed to treat?

Did a heart attack occur within one year of taking Premphase or Prempro?

Were any of the following problems experienced during or after taking HRT medication?

If you suffered any of the above conditions, what was your age when diagnosed?

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Study Against Use of Hormones For Bones

Oct 1, 2003 | UPI Hormone replacement therapy should not be prescribed solely to prevent bone-thinning osteoporosis, according to a study in the Women's Health Initiative.

The study, published in the Journal of the American Medical Association, says the benefit of preventing broken bones is not worth the risks of increased rates of heart disease, breast cancer, strokes and blood clots in the lungs.

The research disputes the policy of the Food and Drug Administration, which permits the use of Prempro, the combined hormone therapy of estrogen and progestin, a form of progesterone, to prevent osteoporosis, the New York Times reported.

FDA officials are scheduled to meet with researchers on Oct. 7 to evaluate the data on osteoporosis. An FDA spokeswoman said it was possible the approved uses of Prempro could change, the Times said.

The medical journal study is based on the same government study that compared 8,102 women who took placebos with 8,506 who took Prempro and found a small increase in the risk of breast cancer, the Times said.

Wyeth, the maker of Prempro, said decisions about hormone use should be made by women and their doctors.

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