http://www.yourlawyer.com/topics/overview/Desmopressin_seizures Sat, 21 Nov 2009 16:41:59 -0800 pixel-app en http://www.yourlawyer.com/articles/read/14869 Fri, 01 Aug 2008 00:00:00 -0700 http://www.yourlawyer.com/articles/read/14869 Desmopressin intranasal spray has been linked to seizures in at least a dozen Australian patients, seven of which were children.  Desmopressin nasal spray is often used to treat bedwetting in children.

Desmopressin is a hormone taken through the nose, by mouth, or given by injection to prevent or control the frequent urination, increased thirst, and loss of water associated with diabetes insipidus (water diabetes). Desmopressin is used also to control bed-wetting and frequent urination and increased thirst associated with certain types of brain injuries or brain surgery. Desmopressin works by acting on the kidneys to reduce the flow of urine.

Last year, the U.S. Food & Drug Administration (FDA) warned that certain patients taking desmopressin are at risk for developing severe hyponatremia that can result in seizures and death.  Hyponatremia is an electrolyte disturbance (disturbance of the salts in the blood) in which the sodium concentration in the plasma is too low.

The warning came after the FDA  reviewed 61 postmarketing cases of hyponatremic-related seizures associated with the use of desmopressin, including 2 fatalities.  Thirty-six cases were associated with intranasal formulations of desmopressin, of which 25 cases occurred in pediatric patients. At the time of last year's FDA alert, the agency said that the use if intranasal Desmopressin was no longer indicated for bedwetting.

Now, Australia's Therapeutic Goods Administration (TGA) says it has received 68 reports of adverse reactions linked to the drug.  There were 17 reports of convulsions and a further 10 of hyponatremia.  The side-effects were mostly seen with the nasal spray formula.

“Of 12 reports of convulsions or hyponatremia following the use of desmopressin nasal spray, seven involved children under 13 years of age,” the TGA said in its latest adverse drug reactions bulletin.  The product will not be removed from sale, but the TGA warned doctors to prescribe the product only when a bed-wetting alarm device has failed to work.

]]> http://www.yourlawyer.com/topics/overview/Desmopressin_seizures Fri, 01 Aug 2008 00:00:00 -0700 http://www.yourlawyer.com/topics/overview/Desmopressin_seizures Desmopressin Seizure Side Effects Lawsuit Attorneys The Food and Drug Administration (FDA) has released a warning concerning the link between the drug Desmopressin and seizures.   Desmopressin side effects include hyponatremia, a low concentration of sodium in the blood, which can result in seizures and death.

Bed Wetting Drug Dangerous Side Effects
Desmopressin is a hormone taken through the nose, by mouth, or given by injection to prevent or control the frequent urination, increased thirst, and loss of water associated with diabetes insipidus (water diabetes). Desmopressin is used also to control bed-wetting and frequent urination and increased thirst associated with certain types of brain injuries or brain surgery. Desmopressin works by acting on the kidneys to reduce the flow of urine.  Desmopressin is commonly inhaled through nose spray or taken orally as tablets in rare cases desmopressin is administered as an injection.

Common Brand Names for Desmopressin:

• DDAVP Injection
• DDAVP Nasal Spray+
• DDAVP Rhinal Tube
• DDAVP Tablets
• Stimate Nasal Spray

Desmopressin Seizure Side Effects Lawsuit Lawyers
If you or a loved one has been injued as the result of Desmopressin side effects including seizures please contact one of our Desmopressin seizure lawsuit attorneys for a free lawsuit case review
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