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Crestor

Crestor Side Effects Lawsuits | Side Effects: Fatal, Disease , Rhabdomyolysis, Kidney Damage, Kidney Failure

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Crestor Side Effects May Be Linked To Kidney Damage Lawsuits

Crestor | Lawsuits, Lawyers | Side Effects: Fatal Disease, Rhabdomyolysis, Kidney Damage, Kidney Failure

Crestor has been linked to kidney damage and kidney failure. On October 22, 2004, the consumer group Public Citizen said twenty-nine patients who took AstraZeneca's cholesterol drug Crestor developed kidney damage. Crestor has also been linked to the potentially fatal disease Rhabdomyolysis.

Consumer group, Public Citizens states, the rate of reported kidney problems is approximately 75 times higher with Crestor than with all other drugs in the same class combined. According to its analysis, there have been 6.4 reports of acute kidney failure or kidney damage for every 1 million Crestor prescriptions filled.

Crestor has been linked to numerous cases of Rhabdomyolysis, a rare muscle destroying disease. Crestor is in the popular family of cholesterol-lowering drugs called Statins. Several years ago Baycol, another popular statin drug, was banned for its link to Rhabdomyolysis.

Crestor Side Effects were Evident Before it was Approved

Crestor was approved by the FDA in August 2003, after a delay because of safety concerns. During FDA studies seven cases of the potentially fatal, muscle-destroying condition Rhabdomyolysis occurred.

These studies also linked Crestor with cases of kidney abnormalities not seen with other Statins. The FDA decided to approve Crestor but at lower dosages. However, records from the FDA and health agencies in Canada and Britain show life-threatening side effects occur even at those lower doses.

Rhabdomyolysis is a serious disorder that causes kidney damage resulting from toxic effects of the contents of muscle cells. Myoglobin is an iron-containing pigment found in the skeletal muscle. When the skeletal muscle is damaged, the Myoglobin is released into the bloodstream. It is filtered out of the bloodstream by the kidneys. Myoglobin may obstruct the structures of the kidney, causing damage such as acute tubular necrosis or kidney failure.

Taking Crestor Might Prevent the Benefits of Exercise

As a statin, Crestor is used to lower cholesterol and prevent heart disease in obese individuals. But research suggests that the supposed benefits of this medication may be counteracted by the fact that can reduce the benefits of exercise in obese patients. In May 2013, researchers at the University of Missouri conducted a study demonstrating this by analyzing 37 individuals who were obese, sedentary and had low fitness levels. The participants, between the ages of 26 and 59, were put on a 12 week exercise regimen; 18 of them took a statin such as Crestor. As it turns out, the cholesterol medication was associated with poorer outcomes. The group not taking the statins increased their cardiorespiratory fitness by an average of 10 percent compared to the 1.5 percent in the statin group. Furthermore, the group not taking statin performed significantly better when it came to skeletal muscle mitochondrial content, which is where the muscles turn oxygen into energy. In the statin group this was decreased 4.5 percent while in the exercise only group there was a 13 percent increase.

Legal Help For Victims Affected By Crestor

If you or a loved one took Crestor and suffered side effects, please fill out the form at the right for a free case evaluation by a qualified drug side effects attorney or call us at 1-800-YOURLAWYER (1-800-968-7529).

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Statin Drugs May Increase Risk for Cataracts, Especially in Diabetics

Jan 1, 2012 | Parker Waichman LLP
People suffering from type 2 diabetes are more likely to suffer an age-related cataract if they are taking a statin drug to lower cholesterol levels. According to a HealthDay News report on a new study from University of Waterloo in Canada, diabetics taking statin drugs are more likely to suffer a cataract than those who weren’t taking one of these cholesterol drugs. Overall, the study authors still believe there is still a clinical benefit to a person suffering from type 2 diabetes who...

Questions Raised Over Expanded Use of Crestor

Mar 31, 2010 | Parker Waichman LLP
Astrazeneca, the maker of Crestor, is about to launch a marketing blitz touting the statin as a preventive medicine.  But some critics think the benefits of using the drug this way don't outweigh its risks.  The new criteria for Crestor was approved by the Food  & Drug Administration (FDA)  last month, after the agency reviewed a clinical study which showed a small reduction of strokes, heart attacks and other “cardiovascular events” among people taking the...

Crestor Does Not Reduce Heart Failure Deaths, Study Says

Nov 29, 2007 | Parker Waichman LLP
Crestor, a cholesterol lowering statin, does not appear to reduce deaths in heart failure patients, according to a new study published in the New England Journal of Medicine.   The results of the 5,000 person CORONA study are a big blow to AtraZeneca, which had hoped to market Crestor as the first statin to show clear benefits in treating chronic heart conditions in the elderly.Crestor was approved by the Food & Drug Administration (FDA) in 2003.  It is a member of a drug...

Study, FDA Differ On Cholesterol Drug Crestor

May 24, 2005 | Washington Post
The powerful cholesterol-lowering drug Crestor is significantly more likely than other statins to cause muscle deterioration that can lead to kidney disease and failure, according to a study in the American Heart Association's journal, Circulation.The conclusion is at odds with the most recent recommendation of the Food and Drug Administration, which in March rejected a petition to remove Crestor from the market. At the time, the FDA said Crestor appeared to be no more dangerous than other...

Study Finds More Side Effects From Crestor Than Other Statins

May 24, 2005 | Los Angeles Times
The widely used cholesterol-lowering drug Crestor has at least twice the incidence of side effects as other drugs in the statin family.The findings suggest that Crestor, manufactured by AstraZeneca, should probably be reserved for patients who have had a hard time lowering their overall cholesterol levels with other statins, said Dr. Richard H. Karas of the Tufts-New England Medical Center in Boston, who led the study.The study was based on adverse reactions to statins reported to the Food and...

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