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Crestor Side Effects

Crestor Side Effects Lawsuit | Side Effects: Fatal Disease Cardiac Myopathy, Rhabdomyolysis, Kidney Damage, Kidney Failure

Crestor Side Effects May Lead To Kidney Damage Lawsuits

Crestor | Lawsuits, Lawyers | Side Effects: Diabetes, Fatal Disease, Cardiac Myopathy, Rhabdomyolysis, Kidney Damage, Kidney Failure, Liver Damage

Have you suffered from Crestor side effects? This popular statin has been linked to a number of serious health problems, including liver damage, kidney damage, cardiac myopathy, diabetes and a muscle disease called rhabdomyolysis. Crestor side effects are so serious that the consumer advocacy group Public Citizen called for the drug to be pulled from the market shortly after it was approved. Yet in 2010, the approved uses of Crestor were expanded to include people without a cholesterol problem.

If you or a loved were diagnosed with, cardiac myopathy, liver damage, kidney damage, diabetes or rhabdomyolysis while taking Crestor, our Crestor side effect lawyers want to hear from you. You may be eligible to obtain compensation by filing a Crestor side effects lawsuit. We are currently offering free lawsuit consultations to all Crestor side effect sufferers. To find out how our Crestor side effect lawyers can help you, please contact us today.

Crestor side effects: Kidney damage and failure, muscle destruction (rhabdomyolysis)

Crestor, known generically as Rosuvastatin, was approved by the Food and Drug Administration (FDA) on August 14, 2003 for the treatment of high-cholesterol. From the start, Crestor proved controversial. Almost immediately, Public Citizen called for Crestor to be removed from the market, warning that it may cause kidney damage and failure, as well as muscle destruction (rhabdomyolysis). In studies before its approval, seven people suffered rhabdomyolysis. Public Citizen also pointed out that Baycol, another statin, was removed from the market in the fall of 2001 after at least 31 reports of fatal rhabdomyolysis.

The FDA rejected Public Citizen's petition for a Crestor ban, but the group continues to push for the drug's removal from the market. Since its approval, Crestor has become the third most popular statin on the market.

In 2010, the FDA approved the expanded use of Crestor in patients without elevated LDL cholesterol but with a combination of other risk factors that put them at increased risk for heart disease. The drug was now indicated for men aged 50 or older and women 60 or older who have elevated C-reactive protein levels (2 mg/L or higher) and at least one additional cardiovascular risk factor such as low HDL cholesterol or high blood pressure.

Under the new criteria, an estimated 6.5 million people in this country who have no cholesterol problems and no sign of heart problems will be deemed candidates for statins like Crestor. Like its initial approval, the approval of this new Crestor indication was controversial. Some patient advocates worried that the risk of Crestor side effects would outweigh its benefits for this new class of patients. There was also debate over the blood test used to identify the new statin candidates. Instead of looking for bad cholesterol, the test measures the degree of inflammation in the body, but there is no consensus in the medical community that inflammation is a direct cause of cardiovascular problems.

Crestor Side Effects

Known Crestor side effects can be serious, and even life threatening. Crestor health problems include:

  • Liver Damage: Crestor liver damage is a significant risk to patients taking this medication and may be even greater in certain patient populations. To avoid Crestor liver damage, patients are advised to undergo blood tests prior to commencing Crestor treatment and periodically thereafter. If any signs of liver problems or persistently high liver enzymes are discovered, doctors may recommend an alternative approach to lowering cholesterol. Certain drugs used concurrently with Crestor may increase the risk of liver damage, including: cyclosporine, Warfarin, gemfibrozil, some antacids, and drugs that lower the body's natural steroid hormone levels or activity like Tagamet or Ketoconazole. Some studies have even shown that eating grapefruit can contribute to Crestor liver damage.
  • Kidney Damage: When Crestor was first approved, the FDA did not approve the drug in stronger proposed doses because of serious Crestor kidney failure risks. In an October 29, 2004 press release, Public Citizen reported that the rate of kidney damage in Crestor patients is 75 times higher than in patients taking other cholesterol drugs. There had been 29 reports of acute renal failure or renal insufficiency. Crestor kidney damage can lead to the need for surgery to remove the kidney and possibly the need for ongoing kidney dialysis treatment.
  • Diabetes: In 2010, a study published in the journal Lancet reported that statins like Crestor are responsible for increasing user risk of developing diabetes by 9 percent. The report analyzed 13 different studies about statin drugs, one of which showed a 25 percent increased risk in developing diabetes in those who take Crestor. One of the studies analyzed by the researchers was the very study the FDA relied upon to approve the expand use of Crestor that same year.
  • Rhabdomyolysis: Rhabdomyolysis is a life threatening case of muscle fiber breakdown that results in the fibers entering circulation that can sometimes lead to kidney damage or failure. In 2005, Public Citizen revealed that from October 1, 2003 through September 30, 2004 , the rate of rhabdomyolysis reports sent to the FDA per million prescriptions filled for Crestor (13.1 reports per million prescriptions) was 6.2 times higher than the rate for all of the other statins combined (2.1 reports per million prescriptions filled). According to a May 2005 study done at Tufts University, patients taking Crestor are eight times more likely to develop rhabdomyolysis, nephropathy, renal failure or proteinuria than patients taking Pravachol, and 6.5 times more likely to develop those complications than patients taking Lipitor. The study, published in Circulation, reported that the adverse event risk was 2.2 fold higher for Crestor versus Zocor.

Legal Help for Victims of Crestor Side Effects

If you or a loved one has taken Crestor and have developed liver damage, kidney damage, diabetes or Rhabdomyolysis, you may have valuable legal rights. To find out how our Crestor side effects lawyers can help you, please fill out our online form, or call 1-800-YOURLAWYER (1-800-968-7529) today.


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Statin Drugs May Increase Risk for Cataracts, Especially in Diabetics

Jan 1, 2012 | Parker Waichman LLP
People suffering from type 2 diabetes are more likely to suffer an age-related cataract if they are taking a statin drug to lower cholesterol levels. According to a HealthDay News report on a new study from University of Waterloo in Canada, diabetics taking statin drugs are more likely to suffer a cataract than those who weren’t taking one of these cholesterol drugs. Overall, the study authors still believe there is still a clinical benefit to a person suffering from type 2 diabetes who...

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