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DES Diethylstilbestrol
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DES (Diethylstilbestrol) Side Effects Lawsuits | Side Effects: Epididymal Cysts, Clear Cell Adenocarcinoma,  Cancers, Genital Abnormalities, Hypospadias, Epic Pregnancy, Miscarriage, Varicocele, Microphallus, Fertility, Lower Sperm Count

DES (Diethylstilbestrol) Side Effects Related To Cancer Lawsuits

DES (Diethylstilbestrol) | Lawsuits, Lawyers | Side Effects; Epididymal Cysts, Clear Cell Adenocarcinoma, Cancers, Genital Abnormalities, Hypospadias, Epic Pregnancy, Miscarriage, Varicocele, Microphallus, Fertility, Lower Sperm Count

DES (Diethylstilbestrol) is a synthetic form of estrogen that was prescribed between 1938 and 1971 to help women with certain complications of pregnancy. DES has been linked to clear cell adenocarcinoma, an uncommon cancer of the vagina or cervix, in daughters of women who used DES during pregnancy. A study published in August 2006 found that women whose mothers took DES during pregnancy have almost double the risk of breast cancer. DES sons are at increased risk of epididymal cysts. Children and grandchildren of women who took DES (Diethylstilbestrol) during pregnancy are at an increased risk of developing significant injuries ranging from rare cancers to genital abnormalities. Parker Waichman Alfonso LLP represents daughters, granddaughters, sons and grandsons who have suffered from side effects of DES.

Clear Cell Adenocarcinoma All DES daughters (women whose mothers took DES while pregnant with them) have a risk of about 1 in 1,000 for a rare cancer of the vagina or cervix called clear cell adenocarcinoma. If you or someone you know has been diagnosed with clear cell adenocarcinoma, we urge you to contact the DES Cancer Network. This cancer is practically non-existent in non-exposed women in this age group. Because of this risk DES daughters need a special exam at least once a year. DES Daughters have an increased risk for infertility. Infertility treatments for DES daughters are, in general, not different from those for other women. DES daughters may want to see a doctor experienced in treating DES-exposed women.

Pregnancy Complications DES Daughters have a higher risk for ectopic pregnancy, miscarriage, and preterm labor and delivery. Most DES daughters can become pregnant and carry their babies to term. However, because of the above risks, all DES daughters (whether they have had previous normal pregnancies or not) require high-risk obstetric care and early confirmation of pregnancy. DES daughters should have their pregnancies confirmed by a health care provider as soon as pregnancy is suspected, and should be seen more frequently throughout their pregnancies.

Reproductive Organ Problems DES daughters have an increased incidence of structural changes in their reproductive organs. These may or may not be linked to pregnancy problems, and are not known to be linked to cancer.

DES Sons and Grandsons

Although less is known about the consequences of DES exposure in men than in women, a number of concerns have been identified. It is important for men who know or suspect they are DES sons to be aware of possible problems and know what to do about them. Most men exposed to DES before birth have no known increased risk of health problems. However, some DES sons do face an increased risk for problems with their genital organs. These range from harmless irregularities to problems that may require medical treatment. Many people, including some doctors, do not know that men can be affected by DES exposure before birth.

  • Epididymal cysts are the most common abnormality in DES sons. The epididymis is a structure on the back of each testicle where sperm are stored. Epididymal cysts are non-cancerous growths that feel like small lumps. They may disappear and recur over time. They do not need to be treated unless they are painful. However, report all lumps to your doctor and perform testicular self-exams on a monthly basis. Testicular problems in some men exposed to DES include both small testicles and undescended testicles. Both of these abnormalities are visible at birth. Men with undescended testicles have an increased chance of developing testicular cancer, even if their mothers didn't take DES. An abnormally small penis (microphallus) occurs more often in DES sons than in other men.
  • Some studies have indicated that testicular varicoceles occur more often in DES sons than in other men. A varicocele is an irregularly swollen or varicose vein on the testicle. This enlarged vein produces a higher temperature than is normal for testicles, and over a period of years can lower the number of normal sperm as a result. Hypospadias is a condition where the opening of the penis is located on the under-surface of the penis rather than at the end.
  • A 1995 study comparing a group of men exposed to DES to a group of men not exposed to DES found that DES had no effect on fertility. The men in this study were all born between 1950 and 1953. The study measured the following factors as indicators of fertility: whether the men had ever impregnated a woman, age at the birth of their first child, average number of children, medical diagnosis of a fertility problem, or length of time to conception in the most recent pregnancy of the female partner. There was no semen analysis done in this study, and thus we do not know whether DES sons have, on average, lower sperm counts. This study indicates that DES does not seem to affect fertility in males.
  • Another study finds that grandsons of women who took the drug diethylstilbestrol, or DES, during pregnancy may be more likely to develop an abnormality of the penis.

Legal Help for DES Victims

If your mother or grandmother took DES (Diethylstilbestrol) during pregnancy, please fill out the form at the right for a free case evaluation by a qualified drug side effects attorney or call us at 1-800-YOURLAWYER (1-800-968-7529).


Daughters face DES drug cancer risk

Aug 7, 2006 |
The daughters of women who took the common pregnancy drug DES (diethylstilboestrol) face an increased risk of developing breast cancer, researchers in the United States have found. The drug, prescribed to women until 1975 to protect against miscarriage and combat morning sickness, has already been found to have increased the risk of breast cancer in mothers who took it. But now it appears the legacy has been passed onto their daughters - with the dangers increasing as they approach menopause,...


Jun 5, 2005 |
In studies involving the drug diethylstilbestrol (DES), the scientific community was compelled to acknowledge the very real possibility that toxic exposure could have trans-generational effects. DES was a synthetic estrogen, manufactured by a number of pharmaceutical companies between the 1940s and 1970s designed to prevent miscarriages. Unfortunately, the drug has had a devastating effect on the female offspring (and possibly even the grandchildren) of women who took DES. Cancer, infertility,...

DES Exposure May Impair Later Function of the Uterus

Mar 9, 2005 | Tulane University
A new study by Tulane University researchers, published in the March edition of Molecular Endocrinology, provides insight into one of the ways diethylstilbesterol (DES) may alter the development of the uterus.DES, a synthetic estrogen, was prescribed to prevent miscarriage in many women who were pregnant between 1941 until 1971. In 1971, DES was banned in the United States due to concerns about the occurrence of cancer and infertility in the daughters of women who took it.Several millions of...

Warning On Miscarriage Drug

Jun 8, 2004 | Queensland Sunday Mail,
All women are urged to contact their mothers today to find out whether they were prescribed a hormone used to prevent miscarriage which has now been linked to cancer and infertility.drug It is believed that up to three generations of Australian women could be at risk of vaginal cancer, infertility and pregnancy complications as a result of the drug, which was widely used in Australia until 1971. Therapeutic Goods Administration chief John McEwen said yesterday: "Women in their 30s and 40s...

Children, Even Grandchildren Affected By DES Legacy

Sep 26, 2003 | The Washington Post
It is with numb precision that Chris Vanselous recounts a long succession of failed pregnancies. She miscarried six babies before the birth of her daughter, Jill, the only child to survive her mother's womb.And for years Vanselous gave credit for that solitary healthy delivery to diethylstilbestrol, or DES, a drug that she and nearly 5 million other would-be mothers were prescribed from 1938 to 1971 under the belief that the synthetic hormone would help them build families where none seemed...

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