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Januvia Side Effects

Januvia Lawsuit | Side Effects : Pancreatitis, Pancreatic or Thyroid Cancer

Januvia Pancreatitis, Pancreatic Cancer Lawsuits | Side Effects : Acute Pancreatitis, Necrotizing Pancreatitis, Pancreatic Cancer, Thyroid Cancer, Death, Hemorrhagic Pancreatitis, Nausea, Vomiting, Anorexia, Persistent severe abdominal pain

Parker Waichman LLP is investigating side effects linked to Januvia, a type 2 diabetes drug made by Merck & Co. Recently, Januvia (sitagliptin) has been linked serious side effects that impact the pancreas, including:

  • Acute Pancreatitis
  • Necrotizing Pancreatitis
  • Hemorrhagic Pancreatitis
  • Pancreatic Cancer
  • Thyroid Cancer
  • Death

The drug side effect lawyers at Parker Waichman LLP are offering free lawsuit consultations to victims of these and other Januvia side effects. If you or a loved one may have suffered an injury due to Januvia, we urge you to contact Parker Waichman LLP today to discuss your potential Januvia side effect lawsuit.

Januvia and Pancreas Side Effects, Pancreatitis, Pancreatic Cancer

Approved by the U.S. Food & Drug Administration (FDA) in 2006, Januvia belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

In September 2009, the FDA announced it was updating the Januvia label to include information on reported cases of acute pancreatitis in patients using the drug. At the time, the agency said it had received 88 reports of post-marketing cases of acute pancreatitis, including two cases of hemorrhagic or necrotizing pancreatitis in patients using sitagliptin, between October 16, 2006 and February 9, 2009. The FDA's analysis found that 19 of the 88 reported cases (21%) of pancreatitis occurred within 30 days of starting sitagliptin or sitagliptin/metformin.  Furthermore, 47 of the 88 cases (53%) resolved once sitagliptin was discontinued.

Patients taking Januvia were advised to pay close attention for any signs or symptoms of pancreatitis including:
  • Nausea
  • Vomiting
  • Anorexia
  • Persistent severe abdominal pain, sometimes radiating to the back.

Chronic pancreatitis is a known risk factor for pancreatic cancer. In the summer of 2011, preliminary results from a study conducted by Dr. Peter Butler, the director of the Larry L. Hillblom Islet

Research Center at the University of California in Los Angeles, found that people taking certain diabetes medications, including Januvia, might face a higher risk of pancreatic cancer. Dr. Butler’s team used data from the FDA's adverse event database involving patients taking new diabetes drugs, including Januvia. Those taking Januvia showed a 2.7-fold increase in pancreatic cancer. Dr. Butlers study was published in the journal Gastroenterology in July 2011.

Januvia and Thyroid Cancer

The thyroid gland secretes hormones responsible for regulating heart rate, blood pressure, body temperature and weight. According to the National Cancer Institute, there were 496,901 people living in the United States with a history of thyroid cancer on January 1, 2009; this includes 108,920 men and 387,981 women. Although most cases if thyroid cancer can be cured with proper treatment, it has a tendency to come back, even if the thyroid has been removed. Signs of thyroid cancer include:

  • A lump on the skin of your neck
  • Changes in voice, voice becomes hoarse
  • Difficulty swallowing
  • Neck and throat pain
  • Swollen lymph nodes

Previous research has found that diabetes medications affecting glucagon-like-peptide-1 (GLP-1) increases the proliferation of precancerous thyroid cells in rates.

Legal Help for Victims of Januvia Side Effects

If you or a loved one suffered pancreatitis or developed pancreatic cancer and or thyroid cancer  that could be associated with Januvia, you may have valuable legal rights. To discuss your case with one of the drug side effect lawyers at Parker Waichman LLP, please fill out our online form, or call 1-800-YOURLAWYER (1-800-968-7529) today.


Januvia Side EffectsRSS Feed

Januvia's cancer risk, other side effects more to consider for diabetics

Jan 2, 2013
As more Americans are diagnosed with diabetes - currently about 1 in 4 already are affected with some form of the disease - they'll all be faced a potentially deadly dilemma: which prescription drug should they and their doctors choose that presents the most benefits and least potentially fatal side effects. A new report published this week at the Web site calls attention to a newer form of type 2 diabetes drug emerging on the market, Januvia. Januvia is manufactured by Merck...

FDA Slams Merck for Failure to Conduct Januvia Pancreatitis Study

Mar 7, 2012 | Parker Waichman LLP
The U.S. Food & Drug Administration has hit Merck & Co. with a warning letter for its failure to conduct a safety study of its type 2 diabetes drug, Januvia.  The study, which was to be conducted with rodents, was meant to assess Januvia's association with pancreatitis. Januvia's label already warns that acute pancreatitis is a possible side effect of the drug, In the warning letter, the FDA says that it informed Merck in 2009 was required to conduct a three-month pancreatic...

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