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Hormone Replacement Therapy
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Which HRT drugs have you taken?

Date you started taking this drug:

Date you stopped taking this drug:

Were any of the following problems experienced during or after taking HRT medication?

If you suffered any of the above conditions, what was your age when diagnosed?

If diagnosed with breast cancer, please indicate details of diagnosis:

Have you been genetically screened for breast cancer?

If you have been screened for breast cancer, please describe results:

Have any family members (sisters, mother, grandmothers) been diagnosed with breast cancer?

If yes, please describe which family member was diagnosed and the type of cancer that was diagnosed:

Please further describe side effects:

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Ortho Prefest

Ortho-Prefest Side Effects May Result In Cancer Lawsuits

Ortho-Prefest | Lawsuits, Lawyers | Side Effects: Endometrial Hyperplasia, Cardiovascular Disease, Thromboembolic Disorders, Uterus Lining Cancer

Ortho-Prefest (Generic: Estradiol & Norgestimate) is a single-tablet prescription hormone replacement therapy (HRT) indicated in women with an intact uterus for the treatment of moderate to severe vasomotor symptoms associated with menopause, treatment of vulvar and vaginal atrophy, and prevention of osteoporosis. Ortho-Prefest was approved by the FDA in 1999 and is manufactured by Ortho-McNeil Pharmaceutical. Estradiol increases the risk of developing endometrial hyperplasia, a condition that may lead to cancer of the lining of the uterus.

Clinical trials tested post-menopausal women and found that Ortho-Prefest was safe and effective in reducing hot flashes and providing relief from vaginal atrophy. The most common side effects in clinical trials over a one-year period were headache and breast pain. These effects were rarely serious enough to cause women to discontinue treatment.

Other side-effects experienced by patients during trials included: back pain, fatigue, flu-like symptoms, abdominal pain, nausea, arthralgias (joint pain), dysmenorrhea (painful menstruation), vaginal bleeding, vaginitis, pharyngitis (inflammation of the throat), sinusitis and upper respiratory infections. Estrogens have been associated with increased risks of serious side effects including thromboembolic disorders, cardiovascular disease, and endometrial carcinoma in post-menopausal women.

Whistle Blown On Johnson & Johnson

Ex Chief Medical Officer, Dr. Joel Lippman, claims that from 1998-2000, his last years at Ortho McNeil, he raised serious health concerns about Ortho-Prefest, a hormonal menopause product, which did not have adequate safety data to provide that it protected against uterine cancer as did other therapies.

Ortho McNeil disregarded Dr. Lippman's concerns and launched the product. Johnson & Johnson, the parent company of Ortho McNeil transferred Dr. Lippman to Ethicon Inc., another J & J subsidiary in 200, shortly after Dr. Lippman made his complaint about Ortho-Prefest.

Legal Rights for Ortho-Prefest Users

If you or a loved one took Ortho-Prefest and suffered side effects, please fill out the form at the right for a free case evaluation by a qualified drug side effects attorney or call us anytime at 1-800-YOURLAWYER (1-800-968-7529).


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Reduced Use of Prempro and Other Hormone Replacement Drugs Linked to Lower Breast Cancer Rates

Dec 14, 2006 | NewsInferno
Breast Cancer Rates in the U.S Dropped 7.2%, Dramatically Reversing Previous Trends Breast cancer rates in the United States dropped 7.2 %, dramatically reversing previous trends which consistently showed rising rates. While the turnaround is surprising news to most, it does not surprise critics of hormone replacement drugs. In 2003, a large federal study linked HRT drugs like Prempro and Premarin, to an increased risk of breast cancer. Within months, millions of women stopped taking...

Chief Medical Officer Blows Whistle On Johnson & Johnson

Dec 13, 2006 |
Johnson & Johnson subsidiary Ethicon fired its chief medical officer because of his insistence that unsafe medical products be recalled, Dr. Joel Lippman claims in Middlesex County Court. Lippman claims that during 15 years in high-ranking medical positions at Ethicon and Ortho McNeil, another J&J subsidiary, Johnson & Johnson repeatedly released or refused to recall dangerous products to which he objected, including the Ortho-Evra birth control patch and Intergel. Both products...

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