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Osteonecrosis of the Jaw (ONJ)
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Osteonecrosis of the Jaw (ONJ)


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ONJ Disease Injury Lawsuits

Osteonecrosis of the Jaw, ONJ | Lawsuits, Lawyers | Disease: Injury, Infection | Side Effects, Prescription Drugs, Fosamax, Bisphosphonates

Osteonecrosis of the jaw (ONJ) has been reported in patients with cancer receiving treatment regimens including Fosamax, a bisphosphonates. Many of these patients were also receiving chemotherapy and corticosteroids. The majority of reported cases have been associated with dental procedures such as tooth extraction. Many had signs of local infection including osteomyelitis.

A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with concomitant risk factors (e.g. cancer, chemotherapy, corticosteroids, poor oral hygiene).

While on treatment, these patients should avoid invasive dental procedures if possible. For patients who develop ONJ while on bisphosphonate therapy, dental surgery may exacerbate the condition. For patients requiring dental procedures, there are no data available to suggest whether discontinuation of bisphosphonate treatment reduces the risk of ONJ. Clinical judgment of the treating physician should guide the management plan of each patient based on individual benefit/risk assessment.

Cases of osteonecrosis (primarily involving the jaws) have been reported in patients treated with bisphosphonates. The majority of the reported cases are in cancer patients attendant to a dental procedure. Osteonecrosis of the jaw has multiple well documented risk factors including a diagnosis of cancer, concomitant therapies (e.g., chemotherapy, radiotherapy, corticosteroids) and co-morbid conditions (e.g., anemia, coagulopathies, infection, pre-existing oral disease).

Although causality cannot be determined, it is prudent to avoid dental surgery as recovery may be prolonged.

Legal Help For Victims Affected By ONJ

If you or a loved one has taken Bisphosphonates drugs and have been diagnosed with Osteonecrosis of the Jaw (ONJ), please fill out the form at the right for a free case evaluation by a qualified defective drug attorney or call us at 1-800-YOURLAWYER (1-800-968-7529).

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Dentists concerned about cases of decaying jaw bones

Dec 19, 2006 | www.tribstar.com
Dentists in Terre Haute are among those in the profession who are becoming more concerned about increasing cases of decaying jaw bones apparently linked to osteoporosis drugs such as Fosamax. The technical name for dying jaw bone is osteonecrosis of the jaw , known as ONJ. Symptoms, which may take weeks or months to appear, include pain, loose teeth, exposed jaw bone in the mouth and drainage, according to the American Dental Association Web site. The drugs being linked to the condition are...

BONE-DENSITY DRUGS CAN KILL JAWS

Jul 5, 2006 | Philadelphia Inquirer
Across the country, dentists have begun asking patients a pointed question before deciding on treatment: Do you take a bone-building medication such as Fosamax? These widely used drugs, called bisphosphonates, have recently been linked to a rare side effect that causes parts of the jawbone to deteriorate and die. The bulk of the 3,000 published cases of jaw osteonecrosis meaning "dead bone" have occurred after dental procedures, mostly in cancer patients on intravenous...

Another Merck Drug Is Under Legal Attack

Jul 5, 2006 | Los Angeles Times
As Merck & Co. defends itself against a deluge of litigation involving its pain reliever Vioxx, the pharmaceutical giant also is fielding the first of what could be another wave of lawsuits involving Fosamax, its second-biggest seller. The emerging litigation targeting the osteoporosis drug, still in its early stages, illustrates how quickly lawyers can organize themselves and assemble prospective plaintiffs after reports of adverse drug effects even when those problems appear to be...

Fosamax risk weighed

Jun 19, 2006 | www.telegram.com
Graphic designer Patricia Korch settled into her oral surgeon’s chair, ready to have a troublesome tooth extracted as part of orthodontia she’d delayed for many years. “You take Fosamax,” he said, studying her medical history form. “Yes, I do,” she replied. He walked around the chair, as if he was going to break bad news to her, she recalled. Then he did. He told her that Fosamax, which she took to stave off the bone-weakening disease osteoporosis, was...

Bone-building drugs linked to bone-rotting side effect

Jun 13, 2006 | Star Ledger
Michael Erlichman walked into his dental office last week and encountered a patient with an unusual but growing problem. An elderly woman was complaining about soreness caused by her dentures, but there was nothing Erlichman could do to relieve her pain. That's because she suffers from a rare jawbone disease that is increasingly being linked to a group of drugs for osteoporosis and cancer. And he noted she'd been taking one of those drugs for several years. "There's more concern about...

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