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Injured by Premphase?

Premphase (Generic: Conjugated estrogens and Medroxyprogesterone acetate) has been linked to the following side effects: dementia, Alzheimer's disease, stroke, blood clots, pulmonary embolisms, lupus and breast cancer. Premphase is a hormone replacement therapy (HRT) prescribed for menopause symptoms.

Approximately 6 million women are taking Prempro to treat post-menopausal hot flashes and other menopause symptoms. However, a recent major study concludes that long-term use of Prempro is dangerous and significantly increases the risk of stroke, blood clots, heart attacks and breast cancer. These results were discovered in the nation's biggest hormone replacement study and were so alarming that the National Institute of Health (NIH) prematurely canceled the study, citing risk to the study's participants. As a result, the study is suggesting that many of the women who use Prempro and other estrogen and progestin combinations should quit taking the medications and talk to their doctors about alternatives.

The evidence is clear that Prempro and other estrogen progestin combinations can harm perfectly healthy women. Women taking Prempro have a 29% higher risk of heart attack, 41% higher risk of stroke and a 26% higher risk of breast cancer. Another study released on May 27, 2003 about the health risks of hormone replacement therapy concluded that the medications can double the risk of dementia and Alzheimer's disease.

Premphase, Premarin and Prempro are manufactured by Wyeth and accounted for about $890 million of the company's $13.9 billion in sales in 2001.

If you or a loved one took Premphase and suffered side effects, please fill out the form at the right for a free case evaluation by a qualified drug side effects attorney.
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Hormone Replacement Therapy Even for Short Periods Raises Breast Cancer Risk

Jan 16, 2008 | Parker Waichman Alonso LLP
U.S. researchers reported this week that hormone replacement therapy (HRT) significantly raises the risk of an uncommon type of breast cancer.  The study found women who took combined estrogen/progestin HRT for three years or more had four times the usual risk of lobular breast cancer.  The study, published in the January issue of Cancer Epidemiology, Biomarkers and Prevention, is one of dozens of studies looking to clarify the dangers of taking HRT to treat menopause symptoms. ...

Hormones can raise breast cancer risk

Apr 19, 2007 | AP
Research on two continents signaled more bad news for menopause hormones, offering the strongest evidence yet that they can raise the risk of breast cancer and are tied to a slightly higher risk of ovarian cancer. New U.S. government numbers showed that breast cancer rates leveled off in 2004 after plunging in 2003 the year after millions of women stopped taking hormones because a big study tied them to higher heart, stroke and breast cancer risks. Experts said the leveling off shows that the...

US drop in breast cancer linked to reduced hormone use

Apr 18, 2007 | AFP
A sharp decline in breast cancer rates in the United States in 2003 could be linked to a reduction in the use of hormone replacement therapy, according to research published Wednesday. The research, based on data from the National Cancer Institute, shows that the breast cancer incidence rates in women in the United States fell 6.7 percent in 2003 from the previous year and have since stabilized. The drop corresponds with a rapid decline in prescriptions for hormone replacement therapy (HRT)...

Reduced Use of Prempro and Other Hormone Replacement Drugs Linked to Lower Breast Cancer Rates

Dec 14, 2006 | NewsInferno
Breast cancer rates in the United States dropped 7.2 %, dramatically reversing previous trends which consistently showed rising rates. While the turnaround is surprising news to most, it does not surprise critics of hormone replacement drugs. In 2003, a large federal study linked HRT drugs like Prempro and Premarin, to an increased risk of breast cancer. Within months, millions of women stopped taking estrogen and progestin pills. Medical researchers has exected about 200,000 cases of breast...

Long-term estrogen users face increased breast cancer risk, study finds

May 9, 2006 | South Florida Sun-Sentinel
Women who take an estrogen hormone supplement longer than 15 years are at a significantly increased risk of developing breast cancer, according to a long-term study of nurses' health published Monday. But the research, reported in the Archives of Internal Medicine, found no increased risk of breast cancer in women who had taken estrogen for less than 10 years. "This says, at least for the shorter-term users, you don't need to panic," said Dr. Wendy Chen, an oncologist and...

More Premphase News

Premphase
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Date you started taking the drug (mm-yyyy):

Date you stopped taking the drug (mm-yyyy):

What condition was this medication prescribed to treat?

Did a heart attack occur within one year of taking Premphase or Prempro?


Were any of the following problems experienced during or after taking HRT medication?










If you suffered any of the above conditions, what was your age when diagnosed?

What was the date of diagnosis?

Please describe diagnosis:

Please describe history of HRT drug prescriptions (please provide date and drug used in chronological order):

If diagnosed with breast cancer, please indicate details of diagnosis:




Have any family members (sisters, mother, grandmothers) been diagnosed with breast cancer?


If yes, please describe which family member was diagnosed and the type of cancer that was diagnosed:

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If you have been screened for breast cancer, please describe results:

Please describe history of blood clots and/or strokes:

Did you ever take Provera?


If yes, did you take Provera while taking Premphase or Premarin?


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