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Injured by Symbyax?

Symbyax is intended for the treatment of depressive episodes associated with bipolar disorder. Symbyax (Generic: Olanzapine and Fluoxetine hci capsules) combines two psychotropic agents, olanzapine (the active ingredient in Zyprexa) and fluoxetine hydrochloride (the active ingredient in Prozac). Olanzapine belongs to the thienobenzodiazepine class. Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI).

Currently, Prozac is used for depression, while Zyprexa is used for schizophrenia as well as the short-term treatment of manic episodes. (Incidentally, Zyprexa is also under consideration by the FDA for long-term maintenance of bipolar disorder.)

Common side effects include:
  • Weight gain
  • Sleepiness
  • Diarrhea
  • Dry mouth
  • Increased appetite
  • Weakness
  • Swelling of hands and feet
  • Sore throat
  • Lack of concentration
Other side effects may include:
  • Severe allergic reactions that cause hives, swelling of your face, eyes, mouth, or tongue, trouble breathing or a rash with fever and joint pain.
  • Strokes and "mini-strokes" called transient ischemic attacks (TIAs). These are more common in elderly patients with dementia.
  • High blood sugar or diabetes.
  • Neuroleptic malignant syndrome (NMS). NMS is a rare, but life-threatening reaction to certain medicines for mental problems.
  • Tardive dyskinesia.
  • Low blood pressure.
  • Seizures
If you or a loved one took Symbyax and suffered side effects, please fill out the form at the right for a free case evaluation by a qualified drug side effects attorney.
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FDA Issues Warning on Drug Use by Elderly

Apr 11, 2005 | AP
Elderly patients with dementia were significantly more likely to die prematurely if taking certain anti-psychotic drugs, the government said Monday in an advisory to health care workers and patients.The Food and Drug Administration is asking manufacturers of atypical anti-psychotic drugs to add to their labeling a boxed warning noting the risks and that the drugs were not approved to treat symptoms of dementia in the elderly.Elderly patients taking the drugs for dementia-related symptoms should...

Deaths with Antipsychotics in Elderly Patients with Behavioral Disturbances

Apr 11, 2005 | www.fda.gov
The Food and Drug Administration has determined that the treatment of behavioral disorders in elderly patients with dementia with atypical (second generation) antipsychotic medications is associated with increased mortality. Of a total of seventeen placebo controlled trials performed with olanzapine (Zyprexa), aripiprazole (Abilify), risperidone (Risperdal), or quetiapine (Seroquel) in elderly demented patients with behavioral disorders, fifteen showed numerical increases in mortality in the...

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