Advil Linked To Skin Disease Childrens Advil is a commonly used painkiller that is designed for children aged two to eleven years, and is available over the counter (OTC). Children’s Advil was introduces in the late 1990s. Childrens Advil has been linked to two often-deadly skin diseases: Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN).
SJS And TEN
Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are two forms of the skin disease that can cause rash, skin peeling, and sores on the mucous membranes. Stevens Johnson Syndrome is an immune-complex–mediated hypersensitivity disorder that may be caused by many drugs, viral infections, and malignancies.
Often, the drugs causing the onset of Stevens Johnson Syndrome and Toxic Epidermal Necrolysis, such as Childrens Advil, did not have warnings placed on their labels until recently. Patients unknowingly took these drugs and many developed the potentially fatal Stevens Johnson Syndrome.