Coreg Side Effects Injury Lawsuits. Coreg is a beta-blocker drug that works by affecting the response to nerve impulses in certain parts of the body. As a result, they decrease the heart’s need for blood and oxygen by reducing its workload, which helps the heart beat more regularly.
The FDA approved Coreg manufactured by GlaxoSmithKline on March 27, 2003. Coreg is used to treat high blood pressure (hypertension), heart failure and current heart attacks. Common side effects of Coreg consist of: tiredness, lightheadedness, dizziness, body or leg swelling, headache, diarrhea, vision changes, joint pain and difficulty falling or staying asleep.
Severe Skin Reactions
During the week of October 24, 2005, The Food & Drug Administration (FDA) issued a label safety change for Coreg. The new label will include a warning for two common severe skin reactions: Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are two forms of the skin disease that can cause rash, skin peeling, and sores on the mucous membranes.
Stevens Johnson Syndrome (SJS) is an immune-complex mediated hypersensitivity disorder that may be caused by many drugs, viral infections, and malignancies. Often, the drugs causing the onset of Stevens Johnson Syndrome (SJS) do not have warnings placed on their labels until recently. Patients unknowingly took these drugs and many developed the potentially fatal Stevens Johnson Syndrome (SJS).Toxic Epidermal Necrolysis (TEN) is a rare condition that causes large portions of the epidermis, the skin’s outermost layer, to disengage from the layers of skin below. Toxic Epidermal Necrolysis (TEN) begins with fever, cough and other nonspecific symptoms, and is soon followed by purplish, bloody-looking lesions on the skin and mucous membranes.
These early lesions, typically found on the head, neck, and upper chest, soon merge and blister. Sheets of epidermis then begin to detach from the skin layers below. In time, the entire surface of the skin may be involved, with detachment of 100% of the epidermis.
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