HRT Can Cause False Negatives During Mammograms. A study published in the May issue of Cancer Epidemiology Biomarkers and Prevention found that women on hormone replacement therapy are more likely to record “false negatives” during routine mammograms than women who are not on hormone replacement therapy.
Hormone Replacement Therapy Makes Tumor Detection More Difficult
Increased breast density (the glandular tissue that appears white on a mammogram), which is high in young women and some of those on hormone replacement therapy makes tumor detection more difficult.
The study results indicate that approximately 5 percent of the women participating in the test who were on hormone replacement therapy had cancers that were not initially detected by mammogram and only 66 percent of the hormone replacement therapy sample had their cancer “at the first round of mammography” as opposed to 82 percent of the non hormone replacement therapy sample.