Parker Waichman LLP

Antibiotic Ceftriaxone Associated with Renal Failure

  Ceftriaxone Linked To Kidney Failure. Ceftriaxone (Rocephin) is an antibiotic medication that is often used to treat childhood infections, but research has also linked this drug to kidney failure in children. Ceftriaxone has been on the market since 1984 and was originally sold by Roche. The antibiotic has been associated with injuries in children […]

Ceftriaxone (Rocephin) Renal Failure

 

Ceftriaxone Linked To Kidney Failure. Ceftriaxone (Rocephin) is an antibiotic medication that is often used to treat childhood infections, but research has also linked this drug to kidney failure in children. Ceftriaxone has been on the market since 1984 and was originally sold by Roche. The antibiotic has been associated with injuries in children in the past. In April 2009, the U.S. Food and Drug Administration (FDA) issued a safety alert warning that the drug should not be used in young infants who are also taking calcium-containing products. As of March 2014, there have been a total of 5 Safety Alerts related to ceftriaxone. Now, evidence suggests that the drug may cause renal failure in children. If your child suffered from renal failure after taking ceftriaxone, contact Parker Waichman LLP today.

Study Links Ceftriaxone to Pediatric Acute Renal Failure (PARF)

On March 24, 2014 a retrospective study published in the journal Pediatrics linked ceftriaxone use to renal stones and renal pediatric acute renal failure (PARF). ‘Ceftriaxone’ has already been linked to biliary pseudolithiasis (pain in the bile ducts), nephrolithiasis (kidney stones) and bladder sludge. Previous research has shown that urine crystals form and cling to renal tubular cells during treatment with the antibiotic.

Researchers analyzed 31 children who developed PARF after ceftriaxone treatment between 2003 and 2012. None of the children in the study had a history of urolithiasis (urinary tract calculi or stones) or nephrolithiasis (kidney calculi or stones). On average, the children were treated with ceftriaxone for 5.2 days before experiencing PARF. The main symptoms were:

  • anuria (unable to urinate adequately)
  • flank pain
  • excessive crying
  • vomiting

Nine children were treated successfully with pharmacotherapy. Retrograde ureteral catheterization was used in 21 children who were resistant to pharmacotherapy. One child needed three sessions of hemodialysis before normal urination occurred.

Based on their findings, the authors of the study concluded “Ceftriaxone therapy in children may cause PARF. Early diagnosis and prompt pharmacological therapy are important in relieving the condition. Retrograde ureteral catheterization is an effective treatment of those who fail to respond to pharmacotherapy.”

A separate analysis conducted by AdverseEvents, Inc. showed that renal failure was associated with ceftriaxone, as well as other similar antibiotic class. Based on this, renal risks should be analyzed for the entire class of third-generation cephalosporin antibiotics, the AdverseEvents Research Team said. The research team also identified a number of adverse events not currently on the drug label, including: drug rash with eosinophilia and systemic symptoms (DRESS), cyanosis, hepatitis, altered state of consciousness, acute respiratory distress syndrome, acute renal failure, respiratory arrest, respiratory failure, wheezing, blood pressure decreased, hepatomegaly (enlarged liver), hypocalcemia (low calcium levels), metabolic acidosis, eyelid swelling, tachycardia, and dyspnea (shortness of breath).

Legal Help for Ceftriaxone Users who Suffered Kidney Failure

If your child suffered from renal failure after taking ceftriaxone, you may have valuable legal rights. For more information, please fill out our online form or call 1-800-YOURLAWYER (1-800-968-7529) to speak with an experienced drug injury attorney today.

What Our Clients Say About Us
We have worked with thousands of clients and we appreciate them and their positive reviews. Here are just a few recent client reviews...
5 Star Reviews 150
After the death of my husband, I decided to call Parker Waichman LLP to investigate the incident surrounding the death. My case was handled in a professional manner. The attorneys and support staff were responsive and attentive to my case. The case was resolved as a result of Parker Waichman's effort for which I am forever thankful. I had a great experience working aside Parker Waichman. All my questions were answered immediately and they were honest. They got back to me on a timely basis and it was a pleasure working with the entire staff. I would recommend them to anyone who is looking for great attorneys and attentive staff.
keturah pyle
8 years ago
5 Star Reviews 150
Aubrey Kendall
6 years ago
5 Star Reviews 150
Gina Viti..My Lawyer with PW LLP.., Gina is an extra special person with Neverending patience..I am OLD SCHOOL..She had to walk me through all necessary steps and did so with knowledge and kind consideration..Not easy to deal with an elder..Gina miraculously got my HEARING going over the phone..Gina is a thorough all encompassing Lawyer..I so much appreciate her and will never forget her
Dorothy Zaharatos
4 weeks ago

Why Choose Us to Help You?

We Take Care of Everything
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
No Recovery = No Legal Fees
We work on a contingency-fee basis, meaning that we only get paid from a portion of your settlement or jury award. If you don't get compensation, you owe us nothing.
Decades of Experience
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
Respected by Our Peers
Judges, insurance adjusters, and fellow attorneys all speak highly of our skills, and we've earned numerous accolades, including a flawless rating from AVVO.
We Have Many Locations To Serve You
We have the experience and the skilled litigators to win your case. Contact us and speak with a real attorney who can help you.
Long Island – Nassau
Parker Waichman LLP
6 Harbor Park Drive
Port Washington, NY 11050
Long Island – Suffolk
Parker Waichman LLP
201 Old Country Road – Suite 145
Melville, NY 11747
New York
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038
Queens
Parker Waichman LLP
118-35 Queens Boulevard, Suite 400
Forest Hills, NY 11375
Brooklyn
Parker Waichman LLP
300 Cadman Plaza West
One Pierrepont Plaza, 12th Floor
Brooklyn, NY 11201
New Jersey
Parker Waichman LLP
80 Main Street, Suite 265
West Orange, NJ 07052
Florida
Parker Waichman LLP
27299 Riverview Center Boulevard
Suite 108
Bonita Springs, FL 34134
Nationwide Service
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038