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Experts: Lens solution still a risk

People Still Using The Recalled Contact Lens Solution. People still using the ReNu with MoistureLoc contact-lens solution need to stop, Kenneth Goins, a University of Iowa clinical associate professor of ophthalmology, said Thursday. And they need to stop now. “I’ve just seen too many patients and too many problems with it,” he said. The product was […]

Lens Solution

People Still Using The Recalled Contact Lens Solution. People still using the ReNu with MoistureLoc contact-lens solution need to stop, Kenneth Goins, a University of Iowa clinical associate professor of ophthalmology, said Thursday.

And they need to stop now.

“I’ve just seen too many patients and too many problems with it,” he said.

The product was recalled May 15 voluntarily by its manufacturer, Bausch & Lomb, but the UI Hospitals and Clinics are still experiencing MoistureLoc effects. Goins said he has approximately a dozen cases presumed to be related to use of the solution.

The company removed it from the market because of its possible link to Fusarium keratitis, a dangerous, sight-threatening fungus infection.

“(The infection) is very difficult to treat,” said Goins, who specializes in corneal and external diseases. “In our series here, about 25 percent of those patients have needed cornea transplants.”

CDC Reported Risk Among MoistureLoc Solutions

The U.S. Centers for Disease Control and Prevention reported an increased risk for the infection among MoistureLoc users, although the cause of the association is not clear.

Christine Sindt, a UI clinical assistant professor of ophthalmology, noticed a problem with the solution almost two years ago when she conducted her own informal study. When MoistureLoc was released in November 2004, she was eager to create a personal assessment of it.

“I always like to test the new products test-drive them, so I can develop an opinion,” Sindt said.

Contact lenses sat soaked in three different solutions overnight. The following day, Sindt examined five volunteers from her office for corneal staining, the presence of dead cells on the eye. Volunteers then wore a pair of the contacts for one to two hours and were examined again.

Sindt, also the director of UIHC’s contact-lens service, said the lenses soaked in MoistureLoc produced an “unusual” amount of staining, named because of a dye’s adherence to dead cells.

She immediately expressed her concern with Bausch & Lomb’s public relations director, who told her he was certain the solution had undergone appropriate studies and had passed. When the director, Fred Edmunds, said the company had not conducted tests that could measure corneal damage over time, she urged him to do so.

“The eye heals itself in about eight hours,” Sindt said. “So the most staining would be noticeable in one to two.”

Then, she waited.

“I felt like at that time I had done my part to voice my concern, and I handled the information appropriately within my own practice when I recommended solutions to my own patients,” Sindt said.

Meanwhile, contact wearers worldwide using the MoistureLoc solution began reporting cases of fungal infections.

Goins said Sindt developed the theory that a new preservative in the formula could get “trapped” in the lens, causing both the corneal staining and infection vulnerability.

“If her theory is true,” he said, “the increased preservative in the lens would lead to a breakdown in corneal epithelial surface cells, thereby allowing pathogens direct access to the cornea, so they may be directly linked.”

Bausch & Lomb, in a report issued May 19, stated it will continue searching for a cause of Fusarium keratitis. Representatives from the corporation could not be reached for comment Thursday afternoon.

With MoistureLoc pulled from store shelves, the threat of its damage remains behind medicine cabinet doors. And until the culprit causing these infections is identified and its inclusion in future solution products permanently banned, Sindt wants only to know one thing: “How long can you beat a dead horse?”

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