Parker Waichman LLP

Cancer Drug, Avastin, Recalled Over Life-Threatening Infections

Hoffmann-La Roche Limited has recalled Avastin (bevacizumab) following cases of necrotizing fasciitis, some fatal, reported in patients receiving the chemotherapy drug in both clinical trials and in the post-marketing setting. Necrotizing fasciitis is a rare, life-threatening infection of the soft tissue ,with rapidly spreading necrosis of superficial fascia and subcutaneous tissue. Necrotizing fasciitis is commonly […]

Avastin_Recalled_Cancer_Drug_InfectionHoffmann-La Roche Limited has recalled Avastin (bevacizumab) following cases of necrotizing fasciitis, some fatal, reported in patients receiving the chemotherapy drug in both clinical trials and in the post-marketing setting.

Necrotizing fasciitis is a rare, life-threatening infection of the soft tissue ,with rapidly spreading necrosis of superficial fascia and subcutaneous tissue. Necrotizing fasciitis is commonly known as flesh-eating disease or flesh-eating bacteria syndrome.

Patients diagnosed with diabetes or who are immunocompromised are at greatest risk of developing necrotizing fasciitis. Roche recommends that Avastin be discontinued and appropriate therapy promptly initiated should a diagnosis of necrotizing fasciitis be received.

Avastin is an injectable cancer medication that works by blocking a protein important for the formation of blood vessels. Tumors rely on blood vessels to receive the nutrients they need to survive; Avastin is believed to work by preventing the formation of new blood vessels that feed the tumor and is approved to treat brain, colorectal, lung, and kidney cancers.

According to Roche, it conducted a comprehensive safety review that identified 52 serious case reports of necrotizing fasciitis between November 1997 and September 2012, worldwide; 17 cases involved patient deaths.

The reported necrotizing fasciitis cases occurred in patients taking Avastin in several cancer indications: 2/3rds were being treated for colorectal cancer; 21 patients had gastrointestinal perforation, fistula formation, or wound healing complications preceding the development of necrotizing fasciitis; and all of the patients were receiving additional chemotherapies other than Avastin. Some patients had no other risk factors.

Hoffmann-La Roche Limited’s Drug Safety Department
is located at 2455 Meadowpine Boulevard,
Mississauga, Ontario, L5N 6L7
and may be reached, toll free, at 1.888.762.4388; by fax at 1.905.542.5864; and by email to: mississauga.drug_safety@roche.com. Roche’s Drug Information Department may be reached toll-free at Hoffmann-La Roche Limited 1.888.762.4388, Monday to Friday, between 8:30 a.m. and 4:30 p.m., Eastern Standard Time.

What Our Clients Say About Us
We have worked with thousands of clients and we appreciate them and their positive reviews. Here are just a few recent client reviews...
5 Star Reviews 150
I speak with Joanne Stevens Nurse Consultant from Parker Waichman LLP she is a pleasure and very compasionate person. so far happy with the people and the firm..
Lona Frawley
5 years ago
5 Star Reviews 150
After suffering pain from a serious injury that occurred during a slip and fall, Parker Waichman gave me Julie Trinidad, which was an effective decision. Ms. Trinidad made my life easier during the stressful time. She provided all answers on a timely manner and did an efficient job with my injury case. Sometimes she provided answers for questions before I could even think of them. She always kept me up to date with all aspects of the case and made sure to see if was in decent condition. I never had to worry because I was in perfect hands and with someone who actually cares about the client (which was me). If anyone I know needs legal advice I would recommend Parker Waichman base off of the great experience and assistance I received from Julie Trinidad. Ms. Trinidad was the best. Merlyn M
Anonymous !
4 years ago
5 Star Reviews 150
I liked how they treated me today, excellent service, keep it up I give you 5 stars, Jorge, Julie, Maryann deserve it
Alexander Morales
2 months ago

Why Choose Us to Help You?

We Take Care of Everything
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
No Recovery = No Legal Fees
We work on a contingency-fee basis, meaning that we only get paid from a portion of your settlement or jury award. If you don't get compensation, you owe us nothing.
Decades of Experience
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
Respected by Our Peers
Judges, insurance adjusters, and fellow attorneys all speak highly of our skills, and we've earned numerous accolades, including a flawless rating from AVVO.
We Have Many Locations To Serve You
We have the experience and the skilled litigators to win your case. Contact us and speak with a real attorney who can help you.
Long Island – Nassau
Parker Waichman LLP
6 Harbor Park Drive
Port Washington, NY 11050
Long Island – Suffolk
Parker Waichman LLP
201 Old Country Road – Suite 145
Melville, NY 11747
New York
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038
Queens
Parker Waichman LLP
118-35 Queens Boulevard, Suite 400
Forest Hills, NY 11375
Brooklyn
Parker Waichman LLP
300 Cadman Plaza West
One Pierrepont Plaza, 12th Floor
Brooklyn, NY 11201
New Jersey
Parker Waichman LLP
80 Main Street, Suite 265
West Orange, NJ 07052
Florida
Parker Waichman LLP
27299 Riverview Center Boulevard
Suite 108
Bonita Springs, FL 34134
Nationwide Service
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038