Parker Waichman LLP

Protease Inhibitors Used to Treat HIV May Increase Diabetes Risk

New research suggests that patients with HIV using protease inhibitor regimens long term may have a higher risk of diabetes. The study, published in Diabetic Medicine, found that the HIV infection by itself does not seem to increase the risk of diabetes, however. To conduct the study, researchers collected data on 6,816 patients infected with […]

protease_inhibitors_may_increase_diabetesNew research suggests that patients with HIV using protease inhibitor regimens long term may have a higher risk of diabetes. The study, published in Diabetic Medicine, found that the HIV infection by itself does not seem to increase the risk of diabetes, however.

To conduct the study, researchers collected data on 6,816 patients infected with HIV at least 18 years old; the median age of the patients was 39 years and 57 percent of the population was male. These patients’ medical records were accessible through the South Carolina Medicaid system and the HIV/AIDS Reporting System Database between 1994 and 2011. For a comparison group, these patients were matched in a 1:1 ratio with non-HIV infected patients who were of similar age, race/ethnicity, gender and length and year of enrollment. The researchers tracked the incidence rate of diabetes in both groups and also recorded the different types of antiretroviral medications used.

The researchers found that in the non-HIV infected group, the incidence rate of diabetes was higher. Additionally, the HIV-infected participants treated with combination antiretroviral therapy had a lower risk of incident diabetes. However, the risk of diabetes was significantly higher in the HIV-infected group associated with long-term exposure to protease inhibitors. In the overall study population, an increased risk of diabetes was linked to female gender, older age, non-white race and pre-existing conditions such as high blood pressure, dyslipidemia, obesity and hepatitis C.

The authors of the study concluded “HIV infection may not be independently associated with increased risk of diabetes. Among HIV-infected persons, exposure to protease inhibitor-based regimens may increase the risk of diabetes. Healthcare providers should make every effort to use combination antiretroviral therapy regimens with a better cardiometabolic profile.”

Protease inhibitors are a type of antiviral drug used to treat HIV/AIDs and hepatitis C. Some examples of protease inhibitors include Fortovase (saquinavir), Norvir (ritonavir), Viracept (nelfinavir) and Agenerase (amprenavir).

What Our Clients Say About Us
We have worked with thousands of clients and we appreciate them and their positive reviews. Here are just a few recent client reviews...
5 Star Reviews 150
Mrs. Josama is phenomenal! She was extremely thorough, attentive, and knowledgeable.
Karema Brown
4 years ago
5 Star Reviews 150
I had a very good experience with the people at PW. No issues at all
Peggy Corrigan
4 years ago
5 Star Reviews 150
Positive: Professionalism , Quality , Responsiveness , Value Tina Morace is extremely reliable, responsive, knowledgeable, accessible and has excellent customer service skills! She is true professional and an asset to Parker Waichman LLP. I highly recommend Tina!
Laura Kelley
3 years ago

Why Choose Us to Help You?

We Take Care of Everything
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
No Recovery = No Legal Fees
We work on a contingency-fee basis, meaning that we only get paid from a portion of your settlement or jury award. If you don't get compensation, you owe us nothing.
Decades of Experience
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
Respected by Our Peers
Judges, insurance adjusters, and fellow attorneys all speak highly of our skills, and we've earned numerous accolades, including a flawless rating from AVVO.
We Have Many Locations To Serve You
We have the experience and the skilled litigators to win your case. Contact us and speak with a real attorney who can help you.
Long Island – Nassau
Parker Waichman LLP
6 Harbor Park Drive
Port Washington, NY 11050
Long Island – Suffolk
Parker Waichman LLP
201 Old Country Road – Suite 145
Melville, NY 11747
New York
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038
Queens
Parker Waichman LLP
118-35 Queens Boulevard, Suite 400
Forest Hills, NY 11375
Brooklyn
Parker Waichman LLP
300 Cadman Plaza West
One Pierrepont Plaza, 12th Floor
Brooklyn, NY 11201
New Jersey
Parker Waichman LLP
80 Main Street, Suite 265
West Orange, NJ 07052
Florida
Parker Waichman LLP
27299 Riverview Center Boulevard
Suite 108
Bonita Springs, FL 34134
Nationwide Service
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038