Parker Waichman LLP

Diabetes Drug Invokana Draws FDA Warning for Risk of Bone Fractures

These medications have been shown to increase the risk of bone fractures. Medications Increase Risk Of Bone Fractures In September, the Food and Drug Administration(FDA) published a safety announcement about the type 2 diabetes drugs Invokana and Invokamet (canagliflozin), advising doctors and patients that these medications have been shown to increase the risk of bone […]

These medications have been shown to increase the risk of bone fractures.

Medications Increase Risk Of Bone Fractures In September, the Food and Drug Administration(FDA) published a safety announcement about the type 2 diabetes drugs Invokana and Invokamet (canagliflozin), advising doctors and patients that these medications have been shown to increase the risk of bone fractures.

The FDA found a new safety announcement necessary because bone fractures have been seen as early as 12 weeks after the patient started taking Invokana, according to the safety announcement. Canagliflozin has also been linked to decreases in bone mineral density of the hip and lower spine.

Invokana and Invokamet labels already contained information about bone-fracture risk in the adverse reactions section. The FDA updated the information under the Warnings and Precautions section of the label after recent clinical trials confirmed the increased risk of fractures.

A clinical trial in elderly patients found that those who had taken canagliflozin for more than two years had reduced bone mineral density in their hips and lower spines. That information was added to the adverse reactions section of the drug’s label.

The FDA advises health care professionals to consider the factors that may contribute to a patient’s fracture risk prior to prescribing canagliflozin, and patients should tell their doctors of any factors that may increase their risk for bone fractures. But the FDA reminds patients that they should not stop or change any diabetes medicine without first discussing their concerns with a health care professional.

These medications are used, in conjunction with diet and exercise

Invokana received FDA approval in 2013. It was the first drug in the new sodium-glucose co-transporter 2 (SGLT-2) inhibitor class of type 2 diabetes medications. In 2014, the FDA approved Invokamet, a combination drug containing canagliflozin and metformin. These medications are used, in conjunction with diet and exercise, to help control blood sugar in adults with type 2 diabetes.

If blood-sugar level is not adequately controlled, the patient can suffer a variety of serious health consequences including blindness, nerve and kidney damage, and heart disease.

This is the second safety warning Invokana has received this year. In May, the FDA issued a safety warning that Invokana could cause ketoacidosis, a dangerous condition in which toxic acids accumulate in the blood, Drugwatch.com reports. If not treated quickly enough, ketoacidosis can be fatal.

The FDA announcement said the agency is continuing to evaluate the risk of bone fractures with other drugs in the SGLT-2 inhibitor class, including Farxiga and Xigduo (dapagliflozin), and Jardiance, Glyxambi, and Synjardy (empaglifozin) to determine if additional label changes or studies are needed.

Need Legal Help Regarding Diabetes Drug Invokana?

The personal injury attorneys at Parker Waichman LLP offer free, no-obligation case evaluations.
For more information, fill out our online contact form or call 1-800-YOURLAWYER (1-800-968-7529)

Our attorney for Invokana Lawsuit is here to help you when you need it the most.

What Our Clients Say About Us
We have worked with thousands of clients and we appreciate them and their positive reviews. Here are just a few recent client reviews...
5 Star Reviews 150
Kelli Alexander is your employee, we have been dealing with her for years. Our case just concluded. Parker Waichman has been a wonderful representative. But Kelli Alexander has been your greatest asset. Our calls promptly returned. Any question answered quicky. She has been kind courteous. and professional, at all times you are lucky to have her in you employment.
Donna Giambalvo
4 years ago
5 Star Reviews 150
My sister was exposed to 9/11 toxins and developed several types of cancer. She chose Parker Waichman to engage the September 11th Victim Compensation Fund and was assigned Tina Morace as her paralegal. Tina was helpful, professional and compassionate in helping us gather medical records and other important information required for the case. Tina was clear and concise in followup queries from the Fund and was quick to respond to our questions. When my sister's condition deteriorated and she passed, Tina was so thoughtful, patient and helpful when I had to address continued Fund followup questions. I will always be thankful for having Tina in our lives. She helped make my sister's last years easier in this aspect. And she was a knowledgeable friend to me, assisting in information gathering and consoling me in my loss. Thank you Parker Waichman. Thank you Tina Morace. Thank you Tina Morace.
Karen Carr
a year ago
5 Star Reviews 150
Positive: Professionalism , Quality , Responsiveness , Value
Diane Volpe
3 years ago

Why Choose Us to Help You?

We Take Care of Everything
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
No Recovery = No Legal Fees
We work on a contingency-fee basis, meaning that we only get paid from a portion of your settlement or jury award. If you don't get compensation, you owe us nothing.
Decades of Experience
Your situation is stressful enough: Let us take on the deadlines, paperwork, investigation, and litigation. We'll handle every detail so you don't have to worry.
Respected by Our Peers
Judges, insurance adjusters, and fellow attorneys all speak highly of our skills, and we've earned numerous accolades, including a flawless rating from AVVO.
We Have Many Locations To Serve You
We have the experience and the skilled litigators to win your case. Contact us and speak with a real attorney who can help you.
Long Island – Nassau
Parker Waichman LLP
6 Harbor Park Drive
Port Washington, NY 11050
Long Island – Suffolk
Parker Waichman LLP
201 Old Country Road – Suite 145
Melville, NY 11747
New York
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038
Queens
Parker Waichman LLP
118-35 Queens Boulevard, Suite 400
Forest Hills, NY 11375
Brooklyn
Parker Waichman LLP
300 Cadman Plaza West
One Pierrepont Plaza, 12th Floor
Brooklyn, NY 11201
New Jersey
Parker Waichman LLP
80 Main Street, Suite 265
West Orange, NJ 07052
Florida
Parker Waichman LLP
27299 Riverview Center Boulevard
Suite 108
Bonita Springs, FL 34134
Nationwide Service
Parker Waichman LLP
59 Maiden Lane, 6th Floor
New York, NY 10038